We present a gamified approach integrating generative AI into undergraduate genetics education. Students work in small groups to create AI-generated patients with unique personalities, demographics, living situations, and genetic conditions, all interconnected. They counsel patients through complex scenarios and complete diagnostic exercises with unknown AI cases, strengthening decision-making, critical thinking, and diagnostic reasoning. Preliminary survey data indicate this approach enhances engagement, ethical reflection, and preparedness for real-world clinician–patient interactions. This model demonstrates how AI can serve as an interactive, gamified pedagogical tool adaptable across disciplines.